According to his son, James Chimphweya Junior, the photojournalist collapsed while on duty at Mfera Trading Centre in Chikwawa on Saturday.
He was rushed to Mfera Health Center and later referred to Chikwawa District Hospital for further treatment.
Chimphweya Junior said his father died Sunday morning of high blood pressure.
Late Chimphweya's body has now been taken to College of Medicine in Blantyre and will later be taken for prayers at Kachere CCAP Church on Monday.
He will be buried at Mfera in Chikwawa on Monday.
Late James Chimphweya was until his death working with the Nation Publication Limited.